SPATIAL DISTRIBUTION AND PREDICTIVE SIGNIFICANCE OF DENDRITIC CELLS AND MACROPHAGES IN ESOPHAGEAL CANCER TREATED WITH COMBINED CHEMORADIOTHERAPY AND PD-1 BLOCKADE

BackgroundThe first clinical study (NCT03671265) of first-line chemoradiotherapy combined with PD-1 blockade showed promising treatment outcomes in locally advanced esophageal squamous cell carcinoma (ESCC).However, partial patients did not respond to the combination treatment.The roles of dendritic cells (DCs) and macrophages in this combination t

Essential oils (EOs) have been used in ethno-medicine as an effective and safe antimicrobial agents for a long time.They have been evaluated for the bactericidal, fungicidal, antiparasitical, Dog-Chews insecticidal, virucidal, medicinal and cosmetics applications.EOs are derived from various species of edible and medicinal plants including herbs an

We introduce a meticulously curated synthetic chart dataset designed to Intakes propel algorithm advancements in data visualization and interpretation.The dataset, tailored for training and testing purposes, encompasses a diverse array of chart types, including but not limited to Area, Bar, Box, Donut, Line, Pie, and Scatter.The data collection pro

Background/Aims: Anaplastic thyroid cancer (ATC), with 25% BRAFV600E mutation, is one of the most lethal human malignancies that currently has no effective therapy.Vemurafenib, a T-Shirts BRAFV600E inhibitor, has shown promise in clinical trials, including ATC patients, but is being hampered by the acquisition of drug resistance.Therefore, combinat